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Multiple ring-enhancing lesions of the brain are one of the most commonly encountered abnormalities on neuroimaging. These can be caused by a variety of infectious, neoplastic, inflammatory or vascular diseases. Distinguishing non-neoplastic causes from neoplastic lesions is extremely important because of misdiagnosis can lead to unwarranted neurosurgery and exposure to toxic chemotherapy or potentially harmful brain irradiation. Diligent clinical evaluation and a battery of tests are required for making a definitive diagnosis. Newer advanced diagnostic techniques, such as diffusion-weighted magnetic resonance imaging (MRI), perfusion-weighted MRI, magnetic resonance spectroscopy, single-photon emission tomography and positron emission tomography may help in establishing the etiology. However, early brain biopsy is often needed because several of these diseases are potentially life-threatening. |
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abscess,intracerebral
abscess,intracerebral,multiple
brain biopsy
central nervous system,infection of
cerebral infarction,septic
chest x-ray,abnormal
embolism,septic
fungal infection
fungal infection,CNS
human immunodeficiency virus type 1
immunocompetent
immunosuppression
lesions too numerous to count
microabscesses,cerebral
microinfarcts
MRI,abnormal
MRI,diffusion weighted
MRI,ring sign
neurologic disease,diagnoses of
practice guidelines
tuberculoma of CNS
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